Body weight fluctuations linked to more deaths in people with coronary artery disease – live5news. com _ charleston, sc _ news, weather, sports

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NEW YORK, April 5, 2017 /PRNewswire-USNewswire/ — Repeated cycles of weight loss and gain may be linked to higher risk for stroke, heart attack, and death in people with pre-existing coronary artery disease, according to a study published online April, 5 in the New England Journal of Medicine.

Led by researchers at NYU Langone Medical Center, the study was the first to measure the effect of “weight cycling” on health outcomes in people with pre-existing heart disease.


Exercise tiger People with the largest weight changes were found to experience 136 percent more strokes, 117 percent more heart attacks, and 124 percent more deaths than those with the smallest shifts in weight.

Those in the high-fluctuation group had weight changes as large as 3.9 kilograms (or roughly 8.6 pounds), while weight varied by around 0.9 kilograms (just under 2 pounds) in the group with the smallest shifts in weight.

“Our findings suggest that we need to be concerned about weight fluctuation in this group that is already at high risk due to coronary disease,” says lead study author Sripal Bangalore, MD, director of the cardiovascular outcomes group in the Cardiovascular Clinical Research Center at NYU Langone.

“Even though this analysis was not designed to find out the causes of increased risk with body weight fluctuations, we need to examine how we can help Americans keep weight off, rather than having it go up and down,” says Bangalore, an associate professor of medicine in the Leon H. Healthy diet chart during pregnancy Charney Division of Cardiology.

The research team reviewed data on 9,509 men and women with coronary artery disease (CAD) who participated in the Treating to New Targets trial, which originally concluded in 2005. Qigong exercises lee holden Study participants were between the ages of 35 and 75. 6 week weight loss plan All had coronary artery disease, high cholesterol levels, and some history of heart problems. Exercise plank Half were being treated with cholesterol-lowering drugs in intensive (versus standard) doses to see if this resulted in fewer deaths. Best diet to get ripped All were monitored for a median of 4.7 years.

The analysis linked shifts in body weight to statistically significant differences in outcomes only in people who were overweight or obese at the beginning of the study, but not for people who started with normal weight. Paleo fried chicken Body weight changes were also strongly linked to an increase in newly diagnosed diabetes, and associations persisted regardless of patients’ average body weight and traditional risk factors for heart disease.

The researchers caution that their re-analysis does not show a cause-and-effect relationship between weight cycling and poor outcomes, but only an association. Weight loss workout plan for women The authors also recognize that they were unable to tell if people lost weight intentionally, unintentionally, or due to illness, or if any eventual heart problems resulted directly from the weight loss, change in weight, or illness.

Dr. 6 week weight loss program Bangalore hopes that the current findings will lead to further study of weight fluctuation in people with coronary artery disease and to the development of related practice guidelines once all the evidence is in.

In the United States, more than 36 percent of American adults are obese, according to the Centers for Disease Control and Prevention. Exercise endorphins Additionally, about half of Americans report they are trying to lose weight, and weight cycling is frequent. Exercise during pregnancy Obesity is known to increase the risk for high blood pressure, high cholesterol, and diabetes, as well as for coronary heart disease.

Besides Dr. T25 diet plan Bangalore, other researchers involved in the study were Rana Fayyad and David DeMicco from Pfizer Inc.; Rachel Laskey from THOR Specialties; Frank Messerli at the University Hospital Bern, Switzerland; and David Waters at San Francisco General Hospital. Losing weight plan The original Treating to New Targets trial is registered online as NCT00327691, and was sponsored by Pfizer.

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